点击化学和生物交反应.pptVIP

点击化学—定义 连接方式(C-X-C)： Generate substances by joining small units together with heteroatom links； 热力学驱动力：high thermodynamic driving force (20 kcal/mol) 过程标准: Modular, wide in scope, give very high yields, generate only inoffensive byproducts that can be removed by non chromatographic methods, stereo-specific, simple reaction conditions, readily available starting materials and reagents, use of no solvent or a solvent that is benign or easily removed, and simple product isolation; 正交试验设计：研究多因素多水平的又一种设计方法，它是根据正交性从全面试验中挑选出部分有代表性的点进行试验特点：“均匀分散，齐整可比”，高效率、快速、经济 * 点击化学和生物正交反应 在生物分子标记中的前所未有的选择