StressIndex-讲义版.ppt

Forty-eight male Sprague-Dawley rats In an isolated, nonperfused, lavaged model of acute lung injury The P-t curve was fitted to: P=a*tb+c Tidal volume and positive end-expiratory pressure were set to obtain (1) a straight P-t curve(b=1) (2) a downward concavity in the P-t curve(b1) (3) an upward concavity in the P-t curve(b1) Ranieri VM, et al. Anesthesiology 2000; 93:1320–8 Ranieri VM, et al. Anesthesiology 2000; 93:1320–8 Ranieri VM, et al. Anesthesiology 2000; 93:1320–8 Stress index is a predictor of a ventilatory strategy that minimizes the occurrence of VILI in an isolated lung model of