安宫牛黄丸中汞-首都医科大学.PDFVIP

2006 10 O ct . 2006 27 5 Journal of Capit al Univ er sit y o f Medical Sciences V ol . 27 N o. 5 安宫牛黄丸中汞砷的存在形式及其吸收与排泄 1 2 2 2 李 袁倬斌 韩树波 朱 敏 1. ; 2. ) ! , , 0 . 003 05% 0. 000 04 % , 0 . 0 33 75% 0 . 000 6 1% 24 h 90 . 195 0% , 24 h 26 . 437 9 % , 24 h 82 . 830 9% 24. 442 0 % 120 h , ! ; ; ; ; ! R 284. 1 The Existent Form of Mercury and Arsenium in Angong Niuhuang Wan and the Absorption and Excreting in Rats 1 2 2 2 Li Jun , Y uan Zhuobin , H an Shubo , Zhu M in ( 1. School of Chemical B iology and Pharmaceutical Sciences, Cap ital Univ ersity of Med ical Sciences; 2. Institute of Ap p lied Chemistry, rad uate School, Chinese Academy of Sciences) ABSTRACT! Ob ective T o detect the exist ent fo rm o f mercury and arsenium in Ang ong N iuhuang Wan A N W) and t he absor ption and ex creting in r ats . Methods T he ex istent for m of mercury w as detected w ith hig h per for mance capillar y electro pho resis . M er cur y and ar senium of v ermilio n and r ealg ar in artif icial g astric and intestinal j uice, and mercury and ar senium ex creted out o f r ats f ed w ith mer cur ic sulf ide, arsenic disulf ide and A N W w er e r espectiv ely tested w ith co ld va pouratomic absor ption spectr ometr y and hydrog en arsenide based metho d. Results M er cur y scutellarin w as detected. M er cur y of verm ilion in artif icial g astric and intest ina l juice respectiv ely w as 0 . 00 3 05% and 0 . 000 04% . A r senium in those M ercury and ar senium of vermilion and realgar w er e r espectiv ely w as 0 . 0 33 75% and 0 . 000 61% . 24 h later, mo