L-肉碱联合西地那非对糖尿病雄性大鼠生殖参数和勃起功能的作用的-研究.pdf

Abstraet TheeffectofL．．carnitinecombinedwithsildenafilon anderectilefunctionindiabetic reproductiveparameter malerats Abstract the of effects Objective：Thisstudyinvestigatedtherapeutic sildenafilaloneorcombinedtreatmenton anderectilefunctionin reproductive diabeticmale itsmechanismfromhormoneandoxidative rats，and stress,to explored evidenceforthetreatmentofLCcombined、航tllsildenafilon experimental provide anderectilefunctionin reproductive diabetes(DM) rat Methods：Toestablish2diabeticmodel of Type byinjectionsaline，group sildenafil B(DMmodel)：saline，groupC(S)：5mg／kg solution，groupD(LC)：300rag／ LC sildenafil+300LCsolution．After kg solution，groupE(S+LC)：5mg／kg mg／kg last functionstatus the erectile testand administration，observed byapomorphine detectionofintracavernous theratswere tookthe pressure(ICP)；thenkilled，we testis， andobservedtheStatusof incauda epididymis，penis spermcount,viability and cellandthe epidid)，midisapoptosisofspermatogenic totalantioxidant e(MDA)，superoxidedismutase(SOD)andcapacity(TAC)in antioxidant testis，epididymis，peniscapacity(TAC)in bloodfromhearttodetectthe testosterone hormone change