维持性血液透析患者抑郁状态及其相关社会因素剖析.docVIP

维持性血液透析患者抑郁状态及其相关社会因素剖析 　　【摘要】目的 探讨维持性血液透析（MHD）患者抑郁症及相关因素的关系。方法 对85例维持性血液透析患者进行Zung抑郁自评量表（SDS）评分，调查抑郁状态在该人群中的患病率；比较抑郁组和非抑郁组的一般情况、透析情况、躯体症状、各实验室指标；用肾脏病生活质量简表（KDQOL-SF）对该人群进行评分，调查抑郁状态对患者生活质量的影响。结果 SDS评分显示该组患者抑郁状态患病率58.8%。抑郁组和非抑郁组的年龄、工作状况、躯体症状、透析方式、内瘘手术次数、透析前血尿酸浓度比较，差异有显著性（p0.05），家庭支持度高、经济状况好的MHD患者，抑郁症发病率低。抑郁组与非抑郁组生活质量分值差异有显著性，KDQOL-SF分值与SDS评分存在负相关(r=-0.871,P0.05)。结论 MHD患者抑郁状态患病率明显高于正常人群。60岁以上、没有工作、无定期血液滤过（HF）或血液透析滤过(HDF)、内瘘手术次数多、透析前血尿酸较高，家庭支持度低、经济状况差的患者抑郁状态患病率高。抑郁组生活质量明显低于非抑郁组。 　　【关键词】维持性血液透析 抑郁症 生活质量 相关因素 　　中图分类号：R473.5文献标识码：A文章编号：1005-0515（2011）10-021-03 　　Depression state and its related factors on maintenance hemodialysis 　　WANGXinjun 　　（et al.The First Hospital Of Shangqiu Henan 476100,China） 　　【Abstract】Objective To investigate the prevalence of depression in with end-stage renal disease (ESRD) undergoing maintenance hemodialysis and analyze the related factors of depression. Method 85 patents with ESRD undergoing hemodialysis were assessed by Zung Self-rating Depression Scale (SDS). The social-family-economic background,dialysis status and bicchemistric indexes of these patients were analyzed. All patients were assessed by the Kidney Disease Quality of Life short from(KDQOL-SF) to investigate the effect of depression on quality of Life.Results 58.8% of patients had SDS score higher than 40,which means the prevalence rate of depression in these patients was 58.8%.These were significant difference in age,employment status,dialysis method,operation times of internal fistula and concentration of uric acid between the depression group and the nondepression group (p0.05).The KDQOL-SF score of the ddepression group was significantly lower than the nondepression group (p0.05),and there exist negative corrlation between the KDQOL-SF score and the SDS score in there patients. Conclusions The prevalence rate of depression in patients with ESRD underqoing maintenance emodialysis was significantly higher than in the general population. patients who over 60 years old