代谢综合征与急性胰腺炎关系的临床分析-内科学(消化系病学)专业论文.docx

新疆医科大学硕士学位论文 新疆医科大学硕士学位论文 PAGE PAGE 1 代谢综合征与急性胰腺炎关系的临床分析 研究生：高鸿亮 导师：谢会忠 教授 摘 要 目的:探讨代谢综合征与急性胰腺炎的关系,及其与急性胰腺炎预后之间的关系, 并进一步研究代谢综合征在预测胰腺病情严重程度、并发症发生率以及急性胰腺炎 预后中的意义。方法:按照 1996 年中华医学会外科学会“AP 临床诊断标准”及 2004 年中华医学会糖尿病分会（CDS）的建议,对新疆医科大学第一附属医院 2007 年 10 月至 2010 年 10 月收集临床资料完整同时收治起病时伴代谢综合征的急性胰腺炎 42 例（MS 组)和不伴代谢综合征的急性胰腺炎 86 例(非 MS 组),对两组年龄、性别、Ranson 评分、Balthazar CT 分级评分、血钙、血 CRP、血氧分压、住院天数、禁食水时间、 腹痛缓解时间、血淀粉酶恢复时间、局部并发症及系统并发症发生率等进行比较,以 了解代谢综合征与急性胰腺炎病情严重程度及预后的关系。结果:MS 组与非 MS 组 年龄、性别比较,差异无统计学意义。MS 组与非 MS 组比较,MS 组 Ranson 评分、 Balthazar CT 分级评分、血 CRP 水平均较高于非 MS 组;血钙和血氧分压水平低于非 MS 组;住院天数、禁食水时间、腹痛缓解时间、血淀粉酶恢复时间明显长于非 MS 组, 局部并发症及系统并发症发生率均高于非 MS 组,差异有统计学意义(P 0.05)。结论: 代谢综合征与急性胰腺炎病情严重程度密切相关,代谢综合征可作为判断急性胰腺炎 的病情严重程度及影响预后的因素之一。 关键词:急性胰腺炎;代谢综合征;关系 The Clinical Analysis of Relationship between Metabolic syndrome and Acute Pancreatitis Postgraduate: Gao Hongliang Supervisor: Xie Huizhong Abstract Objectives: To investigate the clinical analysis of relationship between metabolic syndrome and acute pancreatitis patients.Methods: By 1996 Chinese Medical Association of Surgeons AP clinical diagnostic criteria and 2004 CDS recommendation of First Affiliated Hospital of Xinjiang Medical University, To collect clinical information was also admitted to the onset of acute pancreatitis associated with metabolic syndrome in 42 patients (MS group) and non- metabolic syndrome associated with acute pancreatitis 86 Cases (non-MS group) from October 2007 to October 2010. The two groups for age, sex, Ranson score, Balthazar CT grading score, serum calcium, serum CRP, PaO2, in- hospital days, the fast time,the relief time of abdominal pain and the normalized time of serum amylase days, local complications and the incidence of complications were compared between two groups. Results:MS group and the group for age, sex compared the difference was not statistically significant. Compared with group non-MS, Ranson score, Balthazar CT grading score, serum CRP was higher group non-MS, serum calcium , Pa