天津肿瘤医院1259例肿瘤住院患者抗菌药物应用横断面调查.PDFVIP

现代药物与临床 Drugs Clinic 第 29 卷 第 11 期 2014 年 11 月 ·1303 · 天津市肿瘤医院 1 259 例肿瘤住院患者抗菌药物应用横断面调查 陈 正，韩建庚，王 晨* 天津医科大学肿瘤医院 药学部 国家肿瘤临床医学研究中心 天津市肿瘤防治重点实验室，天津 300060 摘 要：目的 调查分析天津市肿瘤医院抗菌药物的使用情况。方法 采用横断面调查方法，对天津市肿瘤医院 2014 年 3 月 24 日00:00～24:00 所有住院的肿瘤患者抗菌药物使用情况进行调查。结果 1 259 例肿瘤住院患者中，抗菌药物使用率 为 13.19%，单一用药率为 83.13%，二联用药率为 13.86%，三联及以上用药率为 3.01% 。全院治疗性应用抗菌药比例为 78.92%， 预防性应用比例 13.86%，送检率 77.86% 。用药频率（DDDs ）居前三位的依次是碳青霉烯类、第3 代头孢菌素和 β 内酰胺/β 内酰胺酶抑制剂。结论 天津市肿瘤医院住院患者抗菌药物应用基本合理，但个别科室仍存在诸多不合理用药现象，需进一 步加强管理。 关键词：抗菌药物；肿瘤；横断面调查；合理用药 中图分类号：R926 ；R979.1 文献标志码：A 文章编号：1674 - 5515(2014)11 - 1303 - 05 DOI: 10.7501/j.issn.1674-5515.2014.11.026 Cross-sectional survey on utilization of antibiotics among 1 259 inpatients in Tianjin Medical University Cancer Institute and Hospital CHEN Zheng, HAN Jian-geng, WANG Chen Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Department of Pharmacy, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060 Abstract: Objective To carry out the cross-sectional survey on utilization of antibiotics in Tianjin Medical University Cancer Institute and Hospital. Methods In cross-sectional survey, the clinical utilization of all inpatients from 0 to 24 h on March 24th 2014 was surveyed. Results Among 1 259 inpatients, the cross-sectional use rate of antibiotics was 13.19%, of which rate of single-drug was 83.13%, rate of double-drug was 13.86%, and rate of triple-drug and above was 3.01%. The therapeutic use rate of antibiotics was 78.92%, and the prophylactic use rate was 13.86%. Rate of etiological examination for therapeutic medication was 77.86%. The top three antibiotics in the list of DDDs were carbapenems, third generation of cephalosporins, and β-lac