胆管癌分型、危险因素及其相关治疗手段.pdfVIP

Advances in Clinical Medicine 临床医学进展, 2014, 4, 74-80 Published Online December 2014 in Hans. /journal/acm /10.12677/acm.2014.44014 Typing, Risk Factors and Related Treatments of Cholangiocarcinoma Xuehe Zhu, Xudong Liu 1 Inner Mongolia Medical University, Hohhot 2 Affiliated Hospital of Inner Mongolia Medical University, Hohhot Email: 495747315@ nd th th Received: Nov. 2 , 2014; revised: Nov. 20 , 2014; accepted: Nov. 30 , 2014 Copyright © 2014 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Abstract Cholangiocarcinoma (CCA), is a highly malignant tumor, clinically rare and accounting for less than 1% of all malignant tumors. But the number of patients with cholangiocarcinoma in China in- creases year by year, so cholangiocarcinoma research has special significance in our country. De- pending on the anatomical location, cholangiocarcinoma is divided into: hilar cholangiocarcinoma (PHC), the distal bile duct (DCCA) and intrahepatic cholangiocarcinoma (ICCA), among which hilar is the most common. Currently, surgery is the best treatment, but because early diagnosis is diffi- cult, most cases are in the end-stage when diagnosed; therefore, less than 10% of patients are able to tolerate surgery. However the high recurrence rate and low survival rate are still unresolved. With clinical treatment of cholangiocarcinoma deepening, new treatments gradually formed. This article summarizes the results of the analysis of the cholangiocarcinoma typing, clinical manife- stations, risk factors, molecular biological mechanisms and related treatment. Keywords Ch