不动杆菌笑那点事儿.pptVIP

* We confirmed blaOXA-23 with ISAbaI upstream as a promoter to enhance the expression of OXA-23 was the most popular carbapenemase genotypes in China. * for colistin, bactericidal activity was observed at 2×MIC and 4×MIC at 4,8 and 24 h and at 1×MIC at 8 h * However, the hetero-resistance of A. baumannii to colistin should be paid more attention, since several studies reported the evolution of resistance in the process of therapy with colistin. EUCAST和FDA标准有差异；阳性菌无耐药折点 * CRKP：碳青霉烯类抗生素耐药肺炎克雷伯菌 CRAB：碳青霉烯类抗生素耐药鲍曼不动杆菌 * 替加环素组39.6%合并头孢他啶，可能会对结果产生影响。 * 非VAP的HAP * 回顾性研究，33例MDRAB，VAP和BSI未排除，细菌清除患者病死