二维核磁共振谱原理.pptxVIP

2D 核磁共振谱;;;;;;;COSY: Hypothetical Coupling;COSY: 1H-1H Coupling;;Coupling networks can be traced out, as shown in the figure below.? ? ;Table of COSY correlations;;;;What You See In a NOESY. . .;突出表现NOE效应的NOESY谱;;NOESY. . .;NOESY Spectrum of Codeine;Expansion of the upfield region: ;Table of NOEs: ( indicates the more upfield of geminal CH2 protons);;;2 D C-H相关谱（C-H COSY);2 D 远程C-H COSY;Heteronuclear Multiple Quantum Coherence (HMQC) and Heteronuclear Multiple Bond Coherence (HMBC): 2-D inverse H,C correlation techniques that allow for the determination of carbon (or other heteroatom) to