肿瘤血栓临床研究(陆舜).pptVIP

* In this hypothesis, it is proposed that heparins may inhibit the adhesion of circulating tumour cells to platelets, leucocytes, and endothelial cells by binding to cell-adhesion molecules such as P-selectin. * * * This was an experimental study comparing the ability of various heparins to interfere with P-selectin-dependent tumour cell interactions. At equivalent concentrations in terms of anti-factor Xa units, nadroparin, but not enoxaparin, significantly inhibited P-selectin-dependent tumour cell interactions. UFH was also effective in this model. * In a mouse experimental model, the nadr