生物信息学概论案例1.ppt

Biological Sequence Analysis Contents DB Searching the Blast family, pattern hunter, blat, etc. Sequence Alignment Clustalx, Tcoffee, mafft, ProsCons, etc. Sequence Pattern Analysis Sequence Logo, Codon Usage, etc. Protein Sequence Analysis ORF，funcntion，regulatory，strucuture，interaction，etc Phylogenetic analysis MEGA, PAUP, Phylip, Mrbayes, etc. Google Scholar Entrez BLAST Seeding MegaBlast 快速寻找高度相似的序列 主要特点： 比BLAST快数百倍 Large Word size Greedy algorithm 输入输出格式 所有类blast程序都接受fasta格式序列文件 所有类blast程序都输出类似blast的结果文件。 Fasta格式 seq1 CGGCGCTAGCATCGTACACGATCGACACACTGACATCGACACTAGCTAGCGATCGATCGATCGA