偶氮苯基双亲共聚物的溶液到自组装及其多重刺激响应研究-材料工程专业毕业论文.docxVIP

摘要应性，结果表明：pH在6．9～5．5范围内，pH降低，胶束的粒径呈现先增大后减 摘要 应性，结果表明：pH在6．9～5．5范围内，pH降低，胶束的粒径呈现先增大后减 小的趋势，球形核壳结构被破坏，形成不规则的聚合物团聚体；当pH值降至5．5 时，胶束会发生解组装，表现出敏感的pH响应性。这一敏感性来源于聚合物链 中有较多的叔胺基团。UV-Vis、NMR和FTIR研究胶束的还原响应性，双亲共 聚物经Na2S204还原后，偶氮侧基断裂，生成取代苯胺，增加分子链的亲水性， 诱导胶束解组装过程。 5．基于P(POSSMA．CO—AZOMA—CO．DMAEMA)胶束的多重刺激响应性，选 取Nile Red作为疏水模型分子，探索胶束包覆和释放疏水分子的性质。结果表明： 弱酸性或还原性环境均能诱导胶束快速高效地释放出Nile Red分子。 关键词：偶氮苯；POSS；双亲共聚物；聚集诱导荧光发射；多重刺激响应 II 万方数据 AbstractAbstract Abstract Abstract Stimuli—responsive polymeric systems integrating with special responsive moieties can undergo alteration of their chemical structures and physical properties in response to external stimulus．A great deal of work has been done to design multi—stimuli-responsive polymeric systems to enrich applications in the fields of drug controlled release． Azobenzene， as a special light and reduction dual．．stimuli．．responsive moiety undergo trans-cis isomerization under UV light irradiation and cleavage in reducing environment．Owing to dual-stimuli-responses， incorporation of azobenzene into a polymer chains to generate a multi．．stimuli．．responsive amphiphiles have been an active research in the field of macromolecular self-assembly．Here，we synthesized an azobenzene monomer with polymerization activity and prepared a series of azobenzene-based amphiphiles via RAFT polymerization．Furthermore，we researched the self-assembly behaviors of these amphiphiles，fluorescence and release properties of self-assembly nanoaggregates．The main achievements ofthis work are shown as follows： 1．Hydroxyazobenzene HOAZO WaS synthesized by diazo reaction and coupling reaction．Azobenzene monomer AZOMA was prepared by the reaction between HOAZO and methacryloyl chloride．The structures of HOAZO and HOAZO were characterized by NMR，FTIR and MS 2．Azobenzene—based copolymers，P(POSSMA-co—AZOMA—CO‘DMAEMA)， were synthesized with comonomers of AZOMA，POSSMA and DMAEMA via RAFT polymerization．In this way,the light and reduction dual—responsive azo group， pH—responsive tertiar