伊班磷酸钠对老年骨质疏松性股骨粗隆间骨折愈后影响的临床分析.pdfVIP

Abstract Abstract Objective TofindwhetherIbandronatecanaffectthefractureunion,hipjoint function, the stability of internal fixation and the range of bone mineral density following an osteoporotic intertrochanteric fracture in elderly patients, we can treat osteoporotic fracture scientificallyandreasonably. Methods To collect 135 elderly patients who accepted the operation remedy for intertrochantericfractureoffemurandhospitalizedindepartmentoforthopedicsofAffiliated HospitalofHebeiUniversityBetweenSeptember2011andJune2013.BasedonOsteoporosis DiagnosisStandardrecommendedbyWHO,select 120elderlymenwhosefemoralneckbone mineral density( -2. 5).Thesepatientswererandomised to fourgroupsaccordingtothe timingofthecommencementofrisedronatetreatmentaftersurgery:GroupA controlgroup （ ） GroupB(fromoneweek aftersurgery),GroupC(fromonemonthaftersurgery),andGroup D (from three months after surgery). All patients received the application of Iban 2mg intravenous sodium phosphate injection, two consecutive days, once every three months, continuousmedicationforoneyear.Theradiologicaltimetofracturehealingwasassessedas the primary endpoint, and the incidence of complications,including Harris Hip Score, the number of coxa vara, fixation failure and delayed union as the secondary endpoint,and the range of bone mineral density as the final endpoint. .Two observers according to Kappa coefficient to evaluate on the judgement of the reliability of pay-off piece of healing.The statistics processing date all indicated in the form of M±SD( xs ). The comparison of enumeration data uses repeated measurement variance analysis. There was a statistically significant(P0.05)andcorrelationcoefficientshallbeanalyzedbyPearsonmethod. Result Themeantimetofracturehealingpost-operativelyin