针刺同一解剖节段不同经络穴位脑功能磁共振成像研究.PDFVIP

2010;30(6) 南方医科大学学报(JSouthMedUniv) 窑1363窑 针刺同一解剖节段不同经络穴位的脑功能磁共振成像研究 钟治平袁吴珊珊袁刘波袁游玉梅渊广东省中医院影像科袁广东 广州 510120冤 摘要院目的应用磁共振成像技术比较针刺同一解剖节段不同经络的神门穴和养老穴脑功能激活情况遥 方法收集12例 健康志愿者袁实验采用组块刺激模式渊静息阶段与刺激阶段交替出现袁重复3 次袁每个阶段持续60s冤袁按照随机配对数 字表袁分别手法捻转行针针刺右侧的神门穴尧养老穴(捻转角度 180袁频率 1.5Hz)袁使用SPM2对扫描后图像进行后处理 以观察激活图尧激活区的差别遥 结果在校正像情况下(组分析袁FWE袁0.05袁K逸10),神门穴主要激活了右侧额叶的中央 后回BA2尧BA1袁左侧额叶的额下回BA47 和中央后回BA43曰养老穴主要激活了左顶叶的顶下小叶BA40袁右侧额下回 BA45尧BA46遥 结论针刺同一解剖节段不同经络的神门穴和养老穴后脑激活区不同袁 但激活脑区的功能与智能相关袁 这可能与相关经络的循行及脏腑联系密切相关遥 关键词院针刺曰穴位曰经络曰功能磁共振成像 中图分类号院R812 文献标识码院A 文章编号院1673-4254(2010)06-1363-03 Acupunctureattheacupointsofdifferentmeridiansatthesameanatomylevel: astudywith functionalmagneticresonanceimaging ZHONGZhi-Ping,WUShan-Shan,LIUBo,YOUYu-mei DepartmentRadiology,GuangdongProvincialHospitalofTraditionalChineseMedicine,Guangzhou510120,China Abstract:Objective Toinvestigatetheresponseofthespecificbrainfunctionalareasofnormalhumantoacupunctureatthe acupointsofdifferentMeridiansatthesameanatomylevel. Methods Twelvehealthyyoungvolunteerswereenrolledinthis researchandfunctionalmagneticresonance imaging (fMRI) scansweretakenrandomlyinablock design．Duringthe stimulationphase,anacupunctureneedleinsertedinrightShenmen(HT7)orYanglao(SI6) wastwirledatanangleof180毅 andafrequencyofabout1.5Hz.ThecollectedimageswereanalyzedusingSPM2forexploringtheinter-groupdifferencesin bloodoxygenleveldependent(BOLD)responses. ResultsIncreasesinBOLDsignal(groupanalysis,corrected,0.05,K逸10) werefoundmainlyintherightostcentralgyrusofthefrontallobe(BA2,BA1,BA43)andleftinferiorfrontalgyrus(BA47)by acupunctureatHT7,andchieflyintheleftinferiorparietallobule(BA40)andrightinferiorfrontalgyrus(BA45,BA46)by acupunctureat SI6. Conclusion AcupunctureofHT7 and SI6elicitsdifferentBOLDresponsesinsomerelatedcerebral regionscorrelativewithcognition. Keywords:acupuncture;acupoints;meridian;functi