顺铂联合卡培他滨治疗晚期胃癌腹腔积液的疗效及安全性研究.doc

顺钳联合卡培他滨治疗晚期胃癌腹腔积液的疗效及安全性研究 ［摘要］目的探讨顺钳联合卡培他滨治疗晚期胃癌腹腔积液 的疗效及安全性。方法选择我院2014年2月?2015年2月期 间收治的98例晚期胃癌腹腔积液患者作为研究对象，随机将其 分为对照组和观察组。对照组患者单纯采用顺钳进行化疗，观察 组患者采用顺钳联合卡培他滨进行治疗。对比分析两组患者临床 治疗效果及不良反应发生情况。结果观察组患者治疗1个疗程 后和2个疗程后治疗总有效率均明显高于对照组，差异有统计学 意义(P0. 05)o观察组患者在治疗期间不良反应发生率稍高于 对照组，但差异无统计学意义(P0. 05)o结论 顺钳联合卡培他 滨治疗晚期胃癌腹腔积液效果显著，且不良反应少，是一种较为 安全且高效的治疗手段，值得在临床上推广使用。 ［关键词］顺钳；卡培他滨；化疗；胃癌腹腔积液；热疗 ［中图分类号］R735. 2 ［文献标识码］B ［文章编号］ 1673-9701 (2016) 24-0078-03 Department of Tumor with Integrated Chinese and Western Medicine, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang 471000, China [Abstract] Objective To explore the curative effects and safety of cisplatin combined with capecitabine in the patients with advanced gastrie cancer-induced seroper ito neu m. Met hods 98 pati ents with advanced gas trie cancer-induced seroperitoneum who were admitted to our hospital from February 2014 to February 2015 were selected as research subjects. They were randomly assigned to the control group and the observation group? The control group was given cisplatin alone for the chemotherapy, and the observation group was given cisplatin combined with capecitabine for the chemotherapy. Clinical curative effects and adverse reactions were compared and analyzed between the two groups of patie nts. Resu Its The to tai effective rates in the observation group after 1 course of treatment and 2 courses of treatment were both significantly higher than those in the control group, and the differences were statistically significant (P〈0? 05)? The incidence rate of adverse reactions during the treatment in the observation group was slightly higher than that in the control group, and the difference was not statistically significant ( P0.05)? Conclusion Cisplatin combined with capecitabine is significantly effective in the treatment for the patients with advanced gastric cancer-induced seroperitoneum, with few adverse and is worthy of clinical promotion and application. 淋巴瘤属于血液系统恶性疾病，多发生于淋巴结和淋巴组 织，异质性.结外侵袭性