基于聚硫堇多壁碳纳米管共修饰沙丁胺醇电化学传感器构建.PDF

40 2009, Vol. 30, No. 19 食品科学 ※基础研究 1 2 3 3, 吴 芸 ，陈昌云 ，赵 波 ，王正武 * (1. 中国药科大学基础部，江苏南京 211198 ；2.南京晓庄学院化学系，江苏 南京 210017 ； 3. 上海交通大学农业与生物学院食品科学与工程系，上海 200240) 采用循环伏安法研究沙丁胺醇在聚硫堇/ 多壁碳纳米管共修饰金电极上的电化学行为，该电化学传感器对 沙丁胺醇显示出良好的电化学响应，不仅峰电流增加，并且沙丁胺醇的氧化峰电位负移15mV。在最佳测量条件 -7 -6 -7 下，氧化峰电流与沙丁胺醇浓度在4.2 ×10 ～8.3 ×10 mol/L 范围内呈良好线性关系，检出限达2.3 ×10 mol/L 。 沙丁胺醇；硫堇；多壁碳纳米管；电化学传感器 Preparation of Salbutamol Electrochemical Sensor Modified by Polymerized Thionine/multi-wall Carbon Nanotubes 1 2 3 3, WU Yun ，CHEN Chang-yun ，ZHAO Bo ，WANG Zheng-wu * (1. Department of Basic Science, China Pharmaceutical University, Nanjing 211198, China； 2. Department of Chemistry, Nanjing Xiaozhuang University, Nanjing 210017, China ；3. Department of Food Science and Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China) Abstract ：Electrochemical behavior of salbutamol on gold electrode modified by polymerized thionine/multi-wall carbon nanotubes was investigated by cyclic voltammetry method. Good voltammetric response to salbutamol was occurred on this modified electrode, such as peak current enhancement and 15 mV of negative shift in anodic peak potential. Under optimal measurement conditions, a good linear relationship between peak current (Ipa) and salbutamol concentration (C) was showed in -7 -6 -7 the range from 4.2 ×10 to 8.3 ×10 mol/L, and a detection sensitivity could reach 2.3 ×10 mo