toll样受体4表达调控在促红细胞生成素抗炎与抑制大鼠心肌纤维化中的作用与机制研究内科学心血管内科专业论文.docxVIP

AbstractABSTRACT Abstract ABSTRACT Baekground and 0bjective：Cardiovascular disease is the first cause of death in the world．Myocardial fibrosis is the pathological basis of a variety of cardiovascular diseases，such as myocardial infarction and hypertension．It is the key pathological features and reasons of myocardial remodeling．Previous studies have confirmed that myocardial protection of erythropoiesis(EPO)were through the inhibition of myocardial fibrosis．However，the specific mechanism is still unclear． The obj ective of this study is to explore the specific mechanism of EPO against myocardi