包埋技术在天然产物中的应用化学工程与技术专业论文.docxVIP

摘要络合效果较好。此包合物与番茄红素晶体相比，对光、氧、及高温的 摘要 络合效果较好。此包合物与番茄红素晶体相比，对光、氧、及高温的 稳定性均有很大提高。此外，为了提高番茄红素水溶性，制备了番茄 红素．聚乙二醇PEG6000和番茄红素．聚丙乙烯吡咯烷酮PVPl【30固体 分散体，结果显示上述载体与番茄红素摩尔比在4：1时，达到较高的 溶出度。 在提高莱菔硫烷稳定性实验中，主要应用HP．B．CD包合技术， 结果表明莱菔硫烷与HP．13．CD分子主要以l：1计量比络合。通过对 比试验，显示出包合后产物莱菔硫烷／羟丙基．13．环糊精的热稳定性和 化学稳定性有了很大的提高，并对产物进行紫外光谱、红外光谱及核 磁扫描加以验证。 为了提高鞣花酸溶解度，实验中比较多种水溶性载体如羟丙基． B．环糊精HP．p—CD、聚丙乙烯吡咯烷酮PVPk30，聚乙二醇PEG6000、 泊洛沙姆Poloxamerl88等的增溶效果，结果显示PVPk30是比较好的 载体，能提高鞣花酸60倍溶解度，达到1．639 mg／mL，并对产物进 行紫外光谱、红外光谱扫描加以验证。 关键词：番茄红素；莱菔硫烷；鞣花酸；包埋技术 摘要STUDY 摘要 STUDY ON APPLICATIoN oF ENCAPSULATED TECHNOLOGY IN NATURAL PRoDUCTS ABSTRACT With the improvement of living and cultural standards，people are increasingly pursuing healthy living．However,cancer is one of the most serious threat to human health，which has been the most difficult problem in the medical area at the present time．Researches have showed that many natural products contain anti—cancer and antioxidant components such as lycopene(LY)，sulfuraphane(SF)，ellagic acid(EA)and SO on， which have been central issues of study．However,the appl ication and promotion of the natural active ingridients were limited duo to their instability and poor solubility．In this paper，microcapsules，solid dispelrsions and inclusion complexes were researched to improve the stability of lycopene and sulfuraphane，what’S more，to increase the solubility of ellagic in water． Lycopene was extracted from the fermentation of Blakeslea trispora using solvent extraction method．Then，the purification technology of the lycopene-rich oil resin was studied．Alkaline saponification，vacuum concentration and crystallization were performed to get the lycopene at a high purity of 90．1 6％． 摘要In 摘要 In order to improve the stability of lycopene，microcapsules and inclusion complexes of lycopene were prepared．On the one hand，the microencapsulation of lycopene was made by the method of complex oacervation with gelatin—aeaeia system．The effect of various processing parameters including wall materials，the core／wall r