2019EANM／EBJIS／ESR共识：假体关节感染的诊断.pdfVIP

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2019EANM／EBJIS／ESR共识：假体关节感染的诊断.pdf

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European Journal of Nuclear Medicine and Molecular Imaging /10.1007/s00259-019-4263-9 GUIDELINES Consensus document for the diagnosis of prosthetic joint infections: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement) Alberto Signore 1,5 Luca Maria Sconfienza2,3 Olivier Borens4 Andor W. J. M. Glaudemans 5 6 7 8 9 10 Victor Casar-Pullicino Andrej Trampuz Heinz Winkler Olivier Gheysens Filip M. H. M. Vanhoenacker Nicola Petrosillo11 Paul C. Jutte 12 Received: 18 December 2018 /Accepted: 2 January 2019 # The Author(s) 2019 Abstract Background For the diagnosis of prosthetic joint infection, real evidence-based guidelines to aid clinicians in choosing the most accurate diagnostic strategy are lacking. Aim and Methods To address this need, we performed a multidisciplinary systematic review of relevant nuclear medicine, radiological, orthopaedic, infectious, and microbiological literature to define the diagnostic accuracy of each diagnostic technique and to address and provide evidence-based answers on uniform statements for each topic that was found to be important to develop a commonly agreed upon diagnostic flowchart. Results and Conclusion The approach used to prepare this set of multidisciplinary guidelines was to define statements of interest and follow the procedure indicated by the Oxford Centre for Evidence-based Medicine (OCEBM). Keywords Infection diagnosis . Prosthetic joint infection . Imaging . Guideline Abbreviations NSAIDs Nonsteroidal anti-inflammatory drugs PJI Prosthetic joint infection PICO Population/problem – Intervention/indicator – CRP C-reactive p