超声表观积分背散射系数与骨矿密度的相关性分析.pdf

第 32 卷第 1 期 声 学 技 术 Vol.32, No.1 2013 年 02 月 Technical Acoustics Feb., 2013 超声表观积分背散射系数与骨矿 密度的相关性分析 韩海杰，王文斌，许凯亮，他得安，王威琪 （复旦大学电子工程系，上海 200433 ） 摘要：用超声评价骨质状况是近年来骨质疏松诊断方面的研究热 之一。介绍了超声背散射法及其参量表观积分背 散射系数(Apparent Integral Backscatter coefficient, AIB) 的测量及与骨矿密度(Bone Mineral Density, BMD) 的相关性研 究。在体采集了 1087 位志愿者跟骨的超声背散射信号，并用双能 X 射线骨密度仪(Dual X-ray Absorptiometry, DXA) 测得腰椎和髋骨的 BMD 值，然后对 AIB 与 BMD 进行相关性分析。实验结果表明，参数 AIB 与 BMD 显著相关 (R=0.58~0.64, n=1087, p 0.05) ，可被应用于松质骨状况评价。 关键词：松质骨；表观积分背散射系数(AIB) ；骨矿密度(BMD) ；相关性 中图分类号：R455.1 文献标识码：A 文章编号：1000-3630(2013)-01-0029-04 DOI 编码：10.3969/j.issn1000-3630.2013.01.007 Correlation analysis between ultrasonic apparent integral back- scatter coefficient and bone mineral density HAN Hai-jie, WANG Wen-bin, XU Kai-liang, TA De-an, WANG Wei-qi (Department of Electronic Engineering , Fudan University, Shanghai 200433, China) Abstract: The study of ultrasonic assessment of bone status has been a hotspot in the diagnosis of osteoporosis recently. This paper focuses on the correlation analysis between ultrasonic apparent integral backscattering coefficient (AIB) and bone mineral density (BMD). A custom ultrasonic backscatter system was employed to investigate the calcaneus of 1087 volunteers in vivo. The BMD of the volunteers were measured from the spine and hip by the dual X-ray absorptiometry (DXA). The results show that the AIB is obviously correlated to the BMD (R=0.58~0.64, n=1087, p0.05). Thus, the AIB of ultrasonic backscattering signals can be used to assess the stat