高纯度天然右旋龙脑的制备研究.pdfVIP

23 3 Vol. 23 No. 3 2003 9 Chemistry and Industry of Forest Products Sept. 2003 宋永芳, 罗嘉梁 ( 中国林业科学研究院林产化学工业研究所, 江苏 南京210042) SONG Y F : [ Cinnamom um g land ulif er um (Wall) Nees] 70% ~ 80% dd, d GCGC/ MS d, d , d, 11.7~ 2. 0 4 d , d99% d: , 99% , [ ]20 + 37, 205~ 209 , 5 10- 6 , ( As) 2 10- 6 D : ; d; ; :S792. 23; R282.71 :A :0253- 2417(2003) 03- 0011- 04 ST UDY ON PREPARATION OF HIGHPURITY NAT URAL dBORNEOL SONG Yongfang, LUO Jialiang ( Inst it ute of Chem ical I nd ust ry of Forest Prod ucts, CA F , N anj ing 210042, Chi na) Abstract: Crude dborneol was obtained by water vapor distillat ion and sublimation from leaves of Cinnamom um g land ulif er um ( Wall) Nees. In order to prepare highpurity dborneol, experiments were carried out to investigate t he effects of different solvent, solvent amount, times of crystallizat ion and crystallizing time. Highpurity dborneol w as analyzed by GC and GC/ MS, and crystal of dborneol was examined by scanning electron microscopy( SEM ) . Results show ed that gasoline is the best solvent for cryst allizing dborneol, purity of dborneol product w as over 99% using material: solvent rat io 11.7- 2. 0, and crystallizing time 4 days. Analytical data of t he fine natural dbor neol products are: appearance of w hite slice crystals, dborneol content 99% , optical rotat ion [] 20 + 37, melting d point 205- 209 ,heavy metals content 5 millionth and arsenide(As) content 2 millionth. Key words: Cinnamom um gland ulif er um (Wall) Nees; natural dborneol; S