粒细胞集落刺激因子能增强骨髓源单个核细胞治疗下肢缺血的.pptVIP

Objective Can pre-treatment with G-CSF enhance the harvest of BM-MNC，then decrease the BM harvest, but enhance the angiogenic efficacy to treat lower limb ischemia? Retrospective Study * historical control Group 1 Group 2 * G-CSF + MNC MNC Inclusion criteria Severe claudication Rest pain Non-healing ulcer Gangrene Patients were not candidates for endovascular or vascular surgery duo to lack of either suitable conduit lack of suitable anastomotic targets Poor medical condition Exclusion criteria Poorly-controlled diabetes (HbA1C6.5g/dl) Confirmed malignancy during the past 5 years,