课件：儿童侵袭性真菌病.ppt

主要经营：网络软件设计、图文设计制作、发布广告等 公司秉着以优质的服务对待每一位客户，做到让客户满意！ 致力于数据挖掘，合同简历、论文写作、PPT设计、计划书、策划案、学习课件、各类模板等方方面面，打造全网一站式需求 * Various antifungal therapies and approaches may be desirable depending on the stage of the fungal infection (remote, possible, probable, proven culture, or proven tissue diagnosis). Treatment decisions are also based on the length of time the patient has been neutropenic, the degree of granulocytopenia, and the presence of unrelenting fever. The slide represents the factors that influence the decision-making regarding treatment. Therapeutic options run the gamut from prophylaxis when the disease likelihood is remote, to empirical, to pre-emptive, and finally, to specific therapy when there is a proven positive tissue culture. The accompanying signs become more severe as fungal infection progresses. As seen before, the probability of disease increases with the duration of neutropenia. Courtesy of Ben DePauw, MD, EORTC. Slide * N2-108 Antifungal After FDM * The problems associated with diagnosis and treatment of IFI in oncology patients provide the rationale for using preventative strategies. Evidence-based recommendations for preventing exposure to and disease caused by microbial pathogens, including fungi, are detailed in recent joint publications by the Centers for Disease Control and Prevention, the Infectious Disease Society of America, and the American Society of Blood and Marrow Transplantation. Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. Recommendations of CDC, the Infectious Disease Society of America, and the American Society of Blood and Marrow Transplantation. MMWR 2000;49:1-125. * * * * * * * 联合GM检测及CT检查用于早期诊断侵袭性肺真曲霉感染，并可提示开始抗真菌治疗的时机1 肺泡灌洗液GM检测可用于早期诊断侵袭性曲霉感染，且优于血清GM检测及肺泡灌洗液培养或直接检测2 1、Maertens J et al. Clinical Infectious Diseases.2005;41:1242-50. 2、Meersseman W et al. Am j Respir Crit Care Med. 2008;177:27-34. G试验和GM试验联合使用 种属 G试验 GM试验 念珠菌属 ＋ － 镰刀菌属 ＋ － 隐球菌属 － ＋ 曲霉菌属 ＋ ＋ 青霉/拟青霉