产碳青霉烯酶肺炎克雷伯菌的治疗.pptxVIP

替加环素能否用于产碳青酶烯酶肺炎克雷伯菌（CRKP）的严重感染;微生物中的“收藏家”;;耐药进程;泛耐药CRKP;Clinical studies, antimicrobial therapies, and outcomes for patients infected with KPC-producing?K. pneumoniae;Clinical studies, antimicrobial therapies, and outcomes for patients infected with MβL-producing?K. pneumoniae;Regimen A, combination therapy with ≥2 active drugs, one of which was a carbapenem; regimen B, combination therapy with ≥2 active drugs, not including a carbapenem; regimen C, monotherapy with an aminoglycoside; regimen D, monotherapy with a carbapenem; regimen E, monotherapy with tigecycline; regimen F, monotherapy with colistin; regimen G, inappropriate therapy. Regimen A was superior to regimens B, E, F, and G (for A versus B, E, F, and G, the?Pvalue was 0.02, 0.03, 0.0001, and 0.0001, respectively). Regimens B, C, and D were superior to regimen G (for B versus G,?P?= 0.014; for C versus G,?P?= 0.04; and for D versus G,?P?= 0.03).;分析;;;;结论;;参考文献