脑膜瘤mmps和timps的表达意义.docxVIP

脑膜瘤MMPs和TIMPs的表达意义 作者：吴茂春，袁先厚，文志华，江普查 【关键词】脑膜瘤 [Abstract】 AIM： To investigate the relationship between expression of MMP2, MMP 9, TIMP1, TIMP2 in meningiomas and their brain invision. METHODS： The protcin expression of MMP2, MMP9, TIMP1, TIMP2 was detected by immunohistochemistry and the mRNA expression of MMP2, MMP9 was detected by in situ hybridization in 45 patients with meningiomas. RESULTS： The positive rates of the expression of MMP2, MMP9 were 90. 0%(9/10), 90. 0%(9/10) in brain invasive group and 40. 0%(14/35), 42.9%(15/35) in nonbrain invasive group respectively, and the positive rat