恶性肿瘤特异性生长因子的检测及其临床意义.DOC

HYPERLINK /2007/0305/B8CBD741C949T126357.shtml \t _blank 恶性肿瘤特异性生长因子的检测及其临床意义 HYPERLINK / \t _blank 医生在线网 2007-03-05 来源：医生在线 恶性肿瘤特异性生长因子的检测及其临床意义齐鲁肿瘤杂志 1999年第1期第6卷 基础与临床研究作者：刘昌俊　陈珠峰　王民玉　毕峰单位：济南市(250014)　山东省千佛山医院关键词：肿瘤标志物　肿瘤特异性生长因子　恶性肿瘤　　【摘　要】　目的　评价肿瘤特异性生长因子(TSGF)诊断肿瘤的价值及其临床意义。方法　血清中TSGF与显色剂呈显色反应，测其吸光度，查标准曲线，求出TSGF含量，并设健康组、肺感染组和慢性肝炎组作为对照组。结果　83例肿瘤病人血清TSGF含量(71.12±11.03u/ml)显著高于30例健康对照组(P＜0.001)、30例肺感染组(P＜0.001)和30例慢性肝炎组(P＜0.001)。TSGF在肺癌、消化系统和泌尿生殖系肿瘤中的阳性率显著高于CEA阳性率(Pt＞2)。22例化疗有效者血清TSGF含量较化疗前显著降低(P＜0.001)，8例恶化者则显著升高(P＜0.001)。检测肿瘤血清TSGF的敏感性、特异性和准确性分别为91.57%、96.60%和92.04%。结论　TSGF是一种新的敏感性和特异性较高的广谱肿瘤标志物，对肿瘤的辅助诊断、疗效评价和预示肿瘤复发具有重要临床意义。 HYPERLINK / \o 我也要申请橱窗推广 \t _blank HYPERLINK /2013/0514/289FF020C97T418799.shtml \o 降血压有啥妙招 降血压有啥妙招 ? HYPERLINK /2013/0513/6F734916C98T437376.shtml \o 老人血压多少算高 老人血压多少算高 HYPERLINK /2013/0424/FDD0C260C6T438479.shtml \o 高血压神药靠谱吗 高血压神药靠谱吗 ? HYPERLINK /2013/0514/0098D0B1C201T431960.shtml \o 产后如何拯救疤痕 产后如何拯救疤痕 Assay of serum tumor specific growth factor and its clinial significance in malignancies　Liu Changjun,Chen Zhufeng,Wang Minyu,et al.　　Shandong Qianfoshan Hospital,Jinan 250014　　【Abstract】　Objective　To evaluate the value of TSGF in diagnosis of tumor and its clinical significanceMethods　TSGF in serum and chromoparic material cause a chromoparic reaction in a certain condition,then the absorbance can be measured by chromatoptometer.The concentration of TSGF was got from the standard curve.The normal persons,the patients of lung infection and the chronic hepatitis were control groups.Results　The serum TSGF Level of patients with tumor (71.12±11.03u/ml)was significantly higher than that of 30 cases of normal persons(51.23±8.92u/ml,P＜0.001)，30 cases with lung infection (57.12±9.86u/ml,P＜0.001) and 30 cases with chronic hepatitis (51.43±12.38u/ml,P＜0.001).The sensitivity, specificity and accuracy of TSGF in diagnosis of tumor were 91.57%,96.60% and 92.04%, respctively.There was no significant difference in TSGF positive rate among thes