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Antioxidant and Cytoprotective Activities of Ocimum Gratissimum Extracts against Hydrogen Peroxide Induced Toxicity in Human HepG2 Cells YUNG-WEI CHIU 1,2＃, HUNG-JEN LO 3＃, HSIN-YU HUANG4,5, PEI-YU CHAO6,7, JIN-MING HWANG8, PEI-YUN HUANG9 , SHYH-JER HUANG10, JER-YUH LIU10, 11*, TE-JEN LAI2, 12* 1. Emergency department, Tungs’ Taichung MetroHarbor Hospital, Taichung, Taiwan R.O.C. 2. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C. 3. Center of Teacher Education, National Taiwan University of Physical Education and Sport, Taichung, Taiwan, R.O.C. 4. Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan, R.O.C. 5. Department of Early Childhood Education, Wu Feng University, Chiayi, Taiwan, R.O.C. 6. Department of Leisure Industry Management, National Chin-Yi University of Technology, Taichung, Taiwan, R.O.C. 7. Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan, R.O.C. 8. School of Applied Chemistry, Health Care and Management College, Chung Shan Medical University, Taichung, Taiwan, R.O.C. 9. Institute of Biochemistry and Biotechnology, Chung Shan Medical University, Taichung, Taiwan, R.O.C. 10. Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan, R.O.C. 11. Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan, R.O.C. 12. Department of Psychiatry, Chung Shan Medical University Hospital, Taichung, Taiwan R.O.C. ＃ Equal contribution in this paper. *Author for correspondence. +886-4-2473-0022 ext.11010; Fax: +886-4 E-mail: hyhuang2011@.  ABSTRACT Ocimum gratissimum is used as a traditional folk medicine in many countries. The objective of this study was to evaluate the antioxidant activities of the aqueous Ocimum gratissimum extract (OGE) and its cytoprotective activity against hydrogen peroxide induced toxicity in Human HepG2 cells. The results revealed that the total phenolic content reach