冠心病秽浊痰阻证与胰岛素抵抗、血脂异常-中医内科学专业论文.docxVIP

— — PAGE 1— 摘 要 冠心病秽浊痰阻证与胰岛素抵抗、血脂异常的关系研究 研究生：王其军 导师：安冬青 教授 摘 要 目的：通过对 186 例冠心病患者的血脂、空腹血糖、空腹胰岛素及胰岛素抵抗 指数等指标的检测和计算，揭示这些指标与冠心病秽浊痰阻证的关系，为冠心病秽 浊痰阻证的临床辨证提供客观化依据。方法：选取冠心病患者 186 例，分为秽浊痰 阻证组、非秽浊痰阻证组，其中冠心病并糖尿病者 48 例，选取健康对照组 63 例， 观察各组患者一般资料及血脂、空腹血糖、空腹胰岛素、胰岛素抵抗指数的变化。 结果：（1）冠心病秽浊痰阻证组、非秽浊痰阻证组及对照组三组之间 FPG、FINS、 HOMA-IR、TG 、HDL-C、LDL-C 水平比较有统计学意义(P0.05)，TC 水平比较无 统计学意义(P0.05)。（2）冠心病两组间 FINS、HOMA-IR、TG、HDL-C、LDL-C 水平相比有统计学意义(P0.05)，FPG 水平比较无统计学意义(P0.05)。（3）冠心病 并糖尿病患者与单纯冠心病患者比较，FPG 水平无统计学意义(P0.05)，FINS、 HOMA-IR、TG 、HDL-C、LDL-C 水平比较有统计学意义(P0.05)。 结论：(1)冠心 病秽浊痰阻证多有明显的高胰岛素血症、胰岛素抵抗及脂质代谢异常表现,冠心病并 糖尿病患者其胰岛素抵抗及血脂紊乱最为严重。(2)冠心病秽浊痰阻证患者比非秽浊 痰阻证患者的 TG 、LDL-C、空腹胰岛素水平高，而 HDL-C 水平降低。(3)高脂血症、 胰岛素抵抗是秽浊痰阻证的相关危险因素。 关键词：冠状动脉粥样硬化性心脏病；糖尿病；秽浊痰阻证；空腹血糖；空腹胰岛 素；血脂。 新疆医科大学医学硕士学位论文 The Correlativity Study between Insulin resistance and Blood-lipid with the HuiZhuoTan Zu Syndrome of Coronary Heart Disease Postgraduate: Wang Qi-jun Tutor: Pro. An Dong-qing Abstract Objective: From observing the contents of fbg fins homa-ir and blood-lipid, to study the relation of HuiZhuoTanZu syndrome and the non-HuiZhuoTanZu syndrome of coronary heart disease and observe the relation between the HuiZhuoTanZu syndrome of coronary heart disease and fbg fins ir. So as to discuss the difference between the HuiZhuoTanZu syndrome and the non-HuiZhuoTanZu syndrome of coronary heart disease, and provide the microcosmic objective basis for working out the diagnose standard for the coronary heart disease HuiZhuoTanZu syndrome, in order to make its diagnose tend being externalization. Methods: Choose 165 patients of HuiZhuoTanZu syndrome of coronary heart disease, 73 patients of non-HuiZhuoTanZu syndrome,48 patients of HuiZhuoTanZu syndrome of coronary heart disease with 2 type diabetes and 63 healthy people as contrary group, then observe the general data and the contents of fbg fins homa-ir and blood-lipid among four groups. Results: (1)Compare the coronary heart disease HuiZhuoTanZu syndrome group, non-HuiZhuoTanZu syndrome group and h