冠宁软胶囊的药学研究-中药学专业论文.docx

湖北中医学院 湖北中医学院 2004届硕士毕业生学位论又 效液相色谱法测定处方中君药三七的主要成份人参皂苷Rg。的含量，规定每粒含人 参皂苷Rg，不得少于2．5mg。 稳定性考察：为了考察药品的稳定性，确定本品的有效期，考察泡罩包装材 料对药品质量及稳定性的影响，将泡罩包装的本品在温度37—4 ocC 相对湿度75％ 1：加速实验考察三个月，结果表明，在考察期间内，本品的性状、鉴别、崩解时 限、含量测定、微生物限度检查均符合要求．并且泡罩包装材料对本品质量及稳 定性无不良的影响。 主题词：冠宁软胶囊制备工艺质量标准稳定性 塑!!生垦兰堕 塑!!生垦兰堕 !塑!墨篁圭兰些兰兰堡堡兰 AbBtract coronary heart disease is the coimon and frequent iliness o￡ [ardiovascuiar disease．This subject aims at discovering and researching a j1 nd of safe，effective and convenient drug for the disease． Guanning Soft Capsule is made up of Radix Notoginseng，Flos Carthami and Rh]zoma Chuanxiong，which has the effects of promoting blood circJlation r emozlng blood stasls and rel]eving pain，used in blood stasis obstruction， op9』esSlve pa]n 1 n the chest and heart，surgical trauma．swelling and pain caJsed by blood seasls；coronary heart disease，angina pectons．cardiac arrhythmia．soft tissue injury．This product is made into soft capsules in=he bases of clinical application and by choosing and proving of prescription and dosage form．This subject mainly deals with the prepa：ation procedure、quality standard and stability of the prepration． The research on alcoholic exttaction technology of Radix No七oginseng： The main effective element5 of Radix Notoginseng are complicated chemi Ca]s．We extract it by alcoho]．do experiment according to L，[3+l oKhogonaltable contaning four factors--alcohollc consj stency，alcobolic amount，extraction time and frequency that influence the extractiOn ef￡ect， rega=d the amount of total．Radix Notoginseng as evaluation index to choose the mo￡：slj]table condition of exttaction technology．The results show that t．he bes：exttactloll effects are extracting rough power of Radix Notoginseng by 7 0％alcohol for three times which is ten times than the herbal，2 hours once． The research on extraction technology of Flos Carthami liquid：the ：rain effective elements of Flos Carthami is safflor yellow．We extract it by watel，do expez iment accor