金真-北师大讲课北师大ERP课程课件.pptVIP

BOLD fMRI contrast is a complex phenomenon which depends on ?CMR O2 氧耗 ?CBF 血流量 ?CBV 血容积 脑血流动力学反应曲线 Large and small vessel response Large vessel contributions? Does the ratio of negative to positive BOLD contrast change with B0 in such a manner as to suggest more of a smaller vessel contribution to the negative response relative to the positive response? DIP Undershoot -2% -0.5% 1% 5% Hu et al， MRM 37, 877-84, 1997 Early negative BOLD (3-4 sec.) Late positive