功能性精神疾病.ppt

Figure 2. Correlation between COMT met158 allele dosage (0val/val, 1val/met, or 2met/met) and activation by unpleasant stimuli of the ventrolateral PFC ( A), right amygdala ( B), and left dorsal hippocampus ( C). Left, Statistical maps are shown ( p0.05 corrected for volume of mask; cluster size10 voxels). Right, Neural responses of individuals are displayed related to COMT genotype. Individual BOLD responses were extracted from the voxel with the highest t value inside the cluster encircled at the left. * 儿茶酚邻位甲基转移酶(CMOT) COMT基因作为多巴胺功能障碍精神分裂症以及前额页皮质功能障碍的候选基因而被广泛进行关联研究 部分研究小组的结果表明，Val等位基因与精神分裂