合成药物的工艺研究.ppt

Review of Chapter II Design of the synthetic route Typical reactions, Molecular symmetrical, Retro-synthesis, Analogue deduction. Review Selection and evaluation of the synthetic routes - 8 criteria: 1. Synthetic route is succinct, 2. Materials are less and available, 3. Intermediates are easily purified, 4. Reaction condition are easily controlled, 5. The Installment condition is not harsh, 6. 3-wastes are less and efficiently handled, 7. Short workup and convenient process, 8. High yield, low cost, most economic. 第三章 化学合成药物的工艺研究 Chapter 3. Technology Research of Chemical Synth