慢支咳喘宁对COPD模型大鼠支气管肺泡灌洗液及血清MMP 9 TIMP 1的影响-中西医结合临床(呼吸内科)专业毕业论文.docxVIP

慢支咳喘宁对 慢支咳喘宁对 COPD 模型大鼠泡灌洗液及血清 MMP-9、TIMP-1 含量的影响 Abstract Objective：Research and test Manzhikechuanning capsules in COPD by measuring the content of MMP-9 and TIMP-1 in lung tissue and serum to improve the role of prevention and its mechanism in airway remodeling of COPD. Methods ：80 healthy Wistar rats were randomly divided into six groups：the normal group, the model group，low-dose Manzhike chuanning group,moderate-dose Manzhikechuanning group,high-dose Manzhikechuanning group，and Guilongkechuanning group.Rat model with chronic obstructive pulmonary disease was established by exposure to