血清免疫球蛋白表达与咳嗽变异性哮喘患儿预后相关性分析.docVIP

血清C反应蛋白及补体C3水平与急性阑尾炎患儿预后相关性 卢敬东 北京市密云区中医医院儿科门诊北京市101500 [摘要]目的探讨血清中C反应蛋白(CRP)和补体C3水平在急性阑尾炎患儿 预后中的关系。方法 筛选我院收治确诊为急性阑尾炎的32例患儿以及28例健 康儿童血液样本，检测血清CRP和C3水平。对相关的各检测结果分别进行 Pearson直线相关性分析，和Logistic回归分析。结果 急性阑尾炎患儿血清CRP 显著升高(P0.01), C3含量则显著降低(P0.01)；随严重程度升高，CRP显 著增加，C3显著降低。Pearson分析表明，CRP与C3表达呈负相关(P0.05, P0.01)； Logistic分析表明，CRP和C3均与急性阑尾炎诊断具有显著相关性 (P0.01)； ROC曲线分析表明，结果显示CRP和C3在诊断急性阑尾炎中均具 有显著的价值(P0.01)o结论CRP与C3能够诊断儿童急性阑尾炎，能够评估 发病严重程度，指导临床采取合理治疗措施，改善患儿预后。 [关键词]急性阑尾炎；C反应蛋白；补体C3；相关性 Correlation between Serum C Reactive Protein and Complement C3 Levels andPrognosis in Children with Acute Appendicitis [Abstract] Objective Investigate the relationship between serum C reactive protein (CRP) and complement C3 levels and prognosis in children with acute appendicitis? Methods Blood samples from 32 cases with acute appendicitis and 28 healthy children were selected in our hospital and the levels of serum CRP and C3 were determined? Pearson linear correlation analysis and Logistic regression analysis were performed for each test result. Results CRP level was significantly increased (P0.01) in children with acute appendicitis, and the content of C3 was significantly decreased (P0.01). With the increase of severity, CRP was significantly increased, and significantly decreased? Pearson analysis showed that CRP and C3 expression were negatively correlated (P0.05, P0.01); Logistic analysis showed that CRP and C3 were associated with the diagnosis of acute appendicitis was significantly correlated (P0.01); ROC curve analysis showed that, the results showed that CRP and C3 in the diagnosis of acute appendicitis has significant value (P0.01). Conclusion CRP and C3 can be used to diagnose acute appendicitis in children, to assess the severity of the disease, and to guide clinical treatment to improve the prognosis? [Key words] Acute appendicitis; C reactive protein; Complement C3; CoiTclation 急性阑尾炎在儿科临床中是比较常见的急腹症之一，并且占据首位⑴，因其 本身无典型发病症状，同时患儿缺乏自诉能力、体检配合度、治疗依从性差等因 素影响，容易导致阑尾炎临床症状被其他并发症掩盖，极易导致漏诊、误诊2引