汕头大学医学院药理学精品课程 Antiepileptic drugs.pptVIP

Antiepileptic Drugs Department of Pharmacology Zhang Yan-mei Nature of Epilepsy Epilepsy affects about 0.5% of the population. The characteristic event is the seizure, which is often associated with convulsion, but may occur in many other forms. The seizure is caused by an abnormal high-frequency discharge of a group of neurons, starting locally and spreading to a varying extent to affect other parts of the brain. Nature of Epilepsy Seizures may be partial or generalised depending on the location and spread of the abnormal neuronal discharge. The attack may involve mainly motor, sensory or beh