利用CFD模拟研究搅拌釜剪切应力对红豆杉细胞悬浮培养的-精细化工.DOC

基金项目：国家自然科学基金作者简介：刘少杰(1981— 基金项目：国家自然科学基金 作者简介：刘少杰(1981—)，男，副教授，博士，电话：0311E-mail: sjliu16@163.com。 刘少杰, 杜慧丽, 崔笑菲 (河北科技大学 化学与制药工程学院 化学工程系,河北 石家庄 050018) 摘要：首先通过无皂乳液聚合制得聚苯乙烯（PS）种子乳液，再加入苯乙烯磺酸钠继续进行无皂乳液聚合，得到核壳结构的苯乙烯-苯乙烯磺酸钠共聚物微球(PS-NaSS@PS)，然后酸化，得到表面磺酸化的微球(PS-HSS@PS)。以PS-HSS@PS作为可回收的催化剂合成N-(乙氧基亚甲基)苯胺，并与对甲苯磺酸、商品化的强酸阳离子交换树脂的催化性能进行对比。结果表明，PS-HSS@PS的磺酸基含量和加入量对催化性能影响较大，磺酸基含量较高的PS-HSS@PS催化性能优异，收率可以达到97%，其活性优于强酸阳离子交换树脂(收率89%)，与对甲苯磺酸相当(收率98%)，且循环使用性能良好，循环使用5次后，收率请多用数据说话，平均能达到多少？仍可达到97%左右。这段请尽量使用数据说话.中英文一并修改 请多用数据说话，平均能达到多少？ 这段请尽量使用数据说话.中英文一并修改 关键词：苯乙烯-苯乙烯磺酸共聚物微球；无皂乳液聚合；N-(乙氧基亚甲基)苯胺；可回收催化剂 中图分类号：TQ3341 文献标识码：A Synthesis of Ethyl N-phenylformimidate Catalyzed by Surface-sulfonated Polystyrene Microspheres LIU Shao-jie,DU Hui-li,CUI Xiao-fei (College of Chemical Pharmaceutical Engineering, Hebei University of Science Technology, Shijiazhuang 050018, Hebei,China) Abstract: The polystyrene (PS) seed emulsion was firstly prepared by soap-free emulsion polymerization. Styrene-styrene sulfonate copolymer microspheres (PS-NaSS@PS) with core-shell structure was then synthesized through polymerization of sodium p-styrenesulfonate in the PS seed emulsion. Followed by acidizing, surface sulfonated microspheres (PS-HSS@PS) was obtained. Ethyl N-phenylformimidate was synthesized with PS-HSS@PS as a recoverable catalyst. Its catalytic performance was compared with p-toluene sulfonic acid and commercially available strong acidic cation-exchange resin. The results showed that the sulfonic acid group content and the addition amount of PS-HSS@PS had a great influence on the catalytic performance. The catalytic activity of PS-HSS@ PS with high sulfonic acid content was excellent and the yield was up to 97%. The activity of PS-HSS@ PS was higher than that of srong acidic cation-exchange resin (89% of the yield), and comparable to p-toluene sulfonic acid (98% of the yield). Furthermore, PS-HSS@PS had excellent recyclability and the yield