利用肺匀浆驯化后备母猪抵抗肺炎支原体.PDF

Use of lung homogenate to acclimate gilts to Mycoplasma hyopneumoniae 利用肺匀浆驯化后备母猪抵抗肺 炎支原体 Luc Dufresne DVM 卢克·迪弗雷纳，兽医博士 Rebecca Robbins DVM, PhD 丽贝卡·罗宾斯，兽医博士，博士 Seaboard Foods Mhp and the breeding herd 肺炎支原体与繁殖群 • Prevalence of Mhp positive pigs at weaning correlated with Mhp pneumonia • Mhp阳性断奶仔猪的发病率与Mhp肺炎有关 • Colonization of piglets with Mhp is associated with presence of positive lactating sows • 仔猪感染Mhp与阳性哺乳母猪有关 • Vaccination doesn’t prevent Mhp colonization, alter Mhp transmission or consistently reduce Mhp shedding 疫苗接种不能预防Mhp的定植， 改变传播以及持续降低Mhp的排毒量 Mhp and the breeding herd, cont’d 肺炎支原体与繁殖群（接上页） • Success of elimination is inconsistent 成功消 除的结果不一致的 – 3.1 to 20% failure rate 3.1%到20% 的失败率 – Introduction of infected genetic stock and aerosol transmission 引入感染的品种和气溶胶传播 • Entry of naïve gilts into a positive herd or gilts exposed prior to entry are the source of ongoing Mhp infection 阴性后备母猪进入阳 性群或后备进群前感染是Mhp感染的来源 Time of infection highly variable within and between GDUs of an integrated system 在综合生产系统体系后备培育舍内部和之间 的感染事件差异变化明显 比 分 百 性 阳 液 腔 口 周龄 Longitudinal monitoring of Mhp in 4 different GDU flows of a large integrated system. Figure from Anderson, et al 2016. Observations we made 我们观察到的结果 • Growing gilt population no longer Mhp PCR positive 生