生物支架材料矫治漏斗胸畸形-第三军医大学学报.DOCVIP

编号 201106025 刊用形式 论著 猪源生物材料骨重建胸壁缺损及胸壁畸形矫治的疗效观察[ [基金项目] 广东省科技计划项目(2003A3020105) 彭秀凡1,曾伟生1, 乔贵宾1,蒋仁超1,张 伟[通信作者] 张 伟，，电话: (023E-mail: Zhangw1966@126.com （510010 广州，广州军区广州总医院胸外科 [通信作者] 张 伟，，电话: (023E-mail: Zhangw1966@126.com [摘要] 目的 探讨用猪源生物材料骨进行胸壁缺损重建及胸壁畸形矫正的方法及疗效 方法 对2005年12月至2009年12月我院胸外科收治的23例（男性18例，女性5例）患者用猪源生物材料骨进行需胸壁重建或胸壁畸形矫正。其中漏斗胸畸形患者8例，肿瘤切除后胸壁缺损13例，胸骨缺损2例，平均年龄45.8（10～72）岁。8例漏斗胸均为重度漏畸形患者，其中有2例为不对称畸形，全部行胸骨翻转术+猪源生物材料骨胸骨后支撑术；13例为胸壁或肺肿瘤侵犯胸壁手术切除后胸壁缺损，用猪源生物材料骨进行肋骨重建，外被自身软组织；2例为纵隔和胸骨肿切除后胸骨缺损患者，用猪源生物材料骨替代胸骨与两侧前肋及锁骨固定。结果 23例胸壁矫形及重建患者均胸廓成形满意，术后无反常呼吸运动、浮动胸骨、血气胸、感染及材料相关并发症，随访期内未见2次变形；术后X线检查见生物材料与肋骨连接部有骨痂形成。随访1年6个月至5年6个月，全部病例均不需行第2次手术取出生物材料。 结论 用猪源生物材料骨进行胸壁缺损及胸壁畸形的矫治疗效满意，患者无2次手术痛苦。 [关键词] 生物材料; 胸壁缺损；漏斗胸；重建 [中图法分类号] [文献标志码] A The application of porcine-derived arti?cial bone in reconstruction and malformation correction of chest wall Peng Xiufan, Zeng Weisheng, Qiao Guibin, Jiang Renchao，Zhang Wei(Department of Chest Surgery, General Hospital, Guangzhou Military Area, Guangzhou 510010, China) [Abstract] Objective To explore the method and efficacy of chest wall reconstruction and malformation correction using prosthetic materials. Method Twenty-three patients (18 males and 5 females, the age form 10 to 72 years with the mean age of 45.8 years) who were proceeded chest wall reconstruction or chest malformation correction using porcine-derived arti?cial bone were recruited in our inpatient department from December 2005 to December 2009. Of all the patients, eight individuals are severe pectus excavatum including two unsymmetrics, thirteen individuals are chest wall defect, and two individuals are sternum defect. All the severe pectus excavatum patients were used the biomaterial prothesis to support the breast bone after sternal turnover operation. thirteen chest wall defect patients, who were induced by tumor resection of chest wall operation, we