类风湿关节炎和系统性红斑狼疮患者外周血辅助性T细胞17的变化及临床意义的分析-内科学(风湿病)专业论文.docxVIP

安徽医科大学硕士学位论文 安徽医科大学硕士学位论文 PAGE PAGE 7 stimulated in vitro, fixed/rupture and intracellular dye. Flow cytometry(FCM) was used to detect IL-17+ expression in CD4+T cells. Results Peripheral Th17 lymphocytes increased in RA, SLE, AS patients compared with that in normal control(NC) group (2.99±1.51 vs 2.43±0.43 vs 1.93±1.29 vs 0.61±0.27, p0.05). Meanwhile, those of RA are higher than of SLE. However, differences between RA and AS group had no statistical significance as well as those between AS and SLE group. Th17 cells show higher level in active group than in steady group of RA patients. Cor