DNA识别生物传感器和基因芯片中的纳米金和银粒子.pdfVIP

2005 3 Mar. 2005 26 1 Precious Metals Vol. 26, No. 1 DNA 650221 The Gold and Silver Nanoparticles for DNA IdentifyBiosensor and Biochip DONG ShouanTANG Chun ( Kunming Institute of Precious Metals, Kunming, Yunnan 650221, China ) Abstract The gold and silver nanoparticles have the excellent optical, electrical, magnetic and structural properties. The bio-conjugation species produced through combining the gold and silver nanoparticles into the biomolecular surface, due to their size-dependence and dimension being similar to bio macromolecule, are very suitable for acting as a major cycle carrier of the magnetic resonance imaging and the drug release/transport, and a structure skeleton of the tissue culture project. They can also be used in biomolecular identify and label, DNA-sensor and biochip. From the point of biomedicine analysis and the clinical diagnosis, the present paper summarized the application and the development of gold and silver nanoparticles in DNA identify, biosensor, biochip and immunities analysis. Keywords Nanometer technology Gold nanoparticles Silver nanoparticles Review DNA identify Biosensor Biochip / DNA DNA DNA TG146.3 A 1004-0676(2005)01-0053-09 20 80 2004-03-25 (No. 2000 E0008 Z) E-mail: dasw@ 54 26 [12] DNA