微生物学美国IndianaUniversityPurdueUniversity知授课07.pptVIP

Interactions of Phagocytes and Other Immunological Cells BIOL 533 Lecture 7 Production of Ab and Activation of Macrophages and Cytotoxic T Cells T-Dependent T-Independent T-Dependent Activation Extracellular pathogens Digested by macrophage—Ag complexed MHC class II (present only in macrophage and few other cell types) Stimulates helper T cells (TH2) to find B cells, recognize particular peptide fragment?Ab Helper T cells (CD4+ cells; TH1) produces IFN? and activates macrophage T-Dependent Activation Intracellular pathogens Digested when released from dying host cell Peptide Ag presented on