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附件1:特邀专家主题报告
特邀专家主题报告题目1:Application of quantitative and functional phosphoproteomics in study of plant cell signaling
报告人:李凝
报告人简介:
李凝,男,博士,教授,Professor Ning Li graduated from Beijing Forestry College in 1982 and was sent to USA for post-graduate study with a national scholarship in 1983. He obtained a MS and PH.D degree from University of Washington in 1986 and 1989, respectively. After that, Dr. Li obtained a research fellowship from the Plant Science Institute of USDA to work as a research associate in the Plant Molecular Biology Laboratory from 1989 to 1993. He joint the HKUST in1993 and work as an assistant, associate professor to full professor ever since.
His research achievements are the following:
1) Identification of novel ethylene-regulated time-dependent phosphoproteins and putative CTR1 substrates using SILIA-based quantitative and differential phosphoproteomics
2) Establishment of SILIA-based absolute quantitation of isoform of post-translationally modified (PTM) proteins(AQUIP), which will provide practical means to study “combinatorial PTM code” on proteins.
3) Establishment of 15N stable isotope labeling in Arabidopsis (SILIA) protocol for in vivo quantitation of protein PTM, which will provide a large scale of high-throughput data for construction of phosphor-relay-mediated cell signaling network in plants.
4) Discovery of the novel dual-and-opposing effects of ethylene on the shoot negative gravtiropism, which leads to map-based cloning of a family of novel EGY1 gene from Arabidopsis and identification of EIN2-independent alternative ethylene signaling pathways and finding of novel cell signaling components in Arabidopsis using functional and quantitative phosphoproteomics approach.
5) Discovery of cis-cinnamic acid (cis-form) being a new class of growth regulator affecting many aspects of plant growth and development ranging from seed germination, seedling development, flowering and fruit ripening, leading to the molecular cloning of cis-
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