宫颈锥切术后全子宫切除的CINⅢ患者病灶残留相关因素分析.PDF

614 2014 41 6 Cancer Res Prev Treat,2014,Vol.41,No.6 · · 肿瘤防治研究 年第 卷第 期 doi:10.3971/j.issn.1000-8578.2014.06.023 宫颈锥切术后全子宫切除的CIN Ⅲ患者病灶 残留相关因素分析 1 2 1 1 吴绪峰 ，曾 蓉 ，高 晗 ，蔡鸿宁 Predictive Factors for Residual Disease in Subsequent Hysterectomy Following Conization for CIN Ⅲ WU Xufeng1 2 1 1 , ZENG Rong , GAO Han , CAI Hongning 1.Department of Gynecologic Oncology Hubei Maternity and Child Health Hospital Wuhan , , 430070,China 2. Department of Gynecologic Oncology Hubei Cancer Hospital ; , Abstract: Objective To explore predictive factors for post-cone residual disease in subsequent hysterectomy for cervical intraepithelial neoplasia(CIN) Ⅲ. Methods We determined the relationship between residual disease and clinical features, cone marginal status, CIN grade of positive cone margin, conization type by retrospectively reviewing 90 CIN patients who received hysterectomy following cervix conization. Results Ⅲ All cases were followed up for 42-66 months and no recurrence was found. Residual disease was detected in 55 hysterectomy specimen (55/90, 61.11%). There was no significant difference of residual disease incidence between age 40 (33/47, 70.2%) and age 40(22/43, 51.2%), HPV-H positive(32/52, 61.5%) and ≤ negative(1/2, 50.0%), and LEEP(49/78, 62.8%) and CKC group (6/12, 50.0%) (P0.05). The residual disease incidence in patients with positive cone margin (38/53, 71.7%)was higher than that with negative cone margin (17/37, 46.0%,P0.01). The residual disease incidence in patients with cone margin of CIN - (27/33,