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Injury, Int. J. Care Injured 42 (2011) 591–598
Contents lists available at ScienceDirect
Injury
journal homepage: www.else vie r . c om / l o ca t e / i nj u r y
Masquelet technique for the treatment of bone defects: Tips-tricks and future
directions
Peter V. Giannoudis *, Omar Faour, Thomas Goff, Nikolaos Kanakaris, Rozalia Dimitriou
Academic Department of Trauma and Orthopaedic Surgery, Leeds NIHR Biomedical Research Unit, Clarendon Wing, Floor A, Great George Street, Leeds General Infirmary, Leeds LS1 3EX, UK
A R T I C L E I N F O A B S T R A C T
Article history: Reconstruction of diaphyseal bone defects still represents a major clinical challenge. Several approaches
Accepted 17 March 2011 are used with the common objective to regenerate bone loss and restore function. The methods most
commonly used are the vascularised fibula autograft and the Ilizarov bone transfer technique. Recently,
Keywords: Masquelet proposed a procedure combining induced membranes and cancellous autografts. The aim of
Bone defect this article was to briefly describe the technique, to review the current evidence and to discuss the tips
Growth factors and tricks that could help the surgeons to improve outcome. Future directions to increase its
Induced membrane
effectiveness and expand its application are also being discussed. However, predicting the outcome of
Bone repai
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