妈富隆加米非司酮配合归脾丸治疗绝经过渡期功能性子宫出血的临床研究.docxVIP

妈富隆加米非司酮配合归脾丸治疗绝经过渡期功能性子宫 出血的临床研究 郑月芹1李贵奇2周慧敏3 冀屮能源峰峰集团总医院北院区 河北邯郸056201 【摘 要】目的：对比不同给药方案对绝经过渡期功血患者的影响。方法: 将我院收治的146例绝经过渡期功血患者依据用药方案差异分组，其中72例仅 给予米非司酮治疗设为对照组，其余74例采用妈富隆加米非司酮配合归脾丸治 疗设为观察组，对比两组疗效与副反应。结果：两组总有效率分别为93.24%与 80.55%,观察组疗效明显更理想(Plt;0.05)；观察组出血与控制时间、突破性 出血的发生率均明显低于对照组(Plt;0.05)；观察组与对照组副反应率分别为 2.70%与12.50%,差异明显(Plt;0.05)o结论：给予绝经过渡期功血患者采用妈 富隆加米非司酮配合归脾丸治疗，该法疗效确切且安全，深具临床推广价值。 【关键词】妈富隆；米非司酮；归脾丸；绝经过渡期；功血 【屮图分类号】R711.52 【文献标识码】B 【文章编号】1674-8999 (2015) 9-0555-02 Mom rich grand plus of spleen?invigorating pill and mifepristone for the treatment of clinical research at the menopause transition functional uterine bleedi ng [Abstract] Objective:To compare the different dosage regimen in patients with menopause transit!on function. Methods: our hospital 146 cases of menopause transition work differences based on regimen in patients with blood group, of which only given mifepristone treatment to 72 cases of control group, the remaining 74 cases on mom rich grand and cooperate with mifepristone spleen?invigorating pill treatment as observation group, compared two groups of curative effect and side effects. Results: the total effective rate was 93.24% and 93.24% respectively in both groups, the curative effect of observation group was obviously better (P lt; 0.05); Observation group, the incidenee of bleeding and control time, breakthrough bleeding were significantly lower than control group (P lt; 0.05); Observation group and con trol group in the adverse eve nt rates were 2.70% and 12.50%, obvious d iff ere nee (P lt; 0.05). Conclusion: give the men opause transition patie nts using mom rich grand function of spleen-invigorating pill and mifepristone for the treatment, the curative effect and security, profound clinical popularization value? 【Key wordslMom rich gra nd; Mifeprist one; Spleen-invigorati ng pill; Meno pause transition; The work of blood 功能性子宫出血(简称功血)是由于神经内分泌失调引起的子宫内膜异常出 血，为非器质性疾病，一般分为无排卵型和排卵型两大类[1-2]o无排卵型在功 血发病率中所占比例据相关资料统计发现其已超过80%,该病主要发作于女性青 春期与绝经期间，以无规律性的