毕业论文--青海西宁地区乙肝调查报告及血清标志物分析.docVIP

本科毕业论文（设计） 青海西宁地区乙型肝炎病毒感染现状及其血清标志物分析 PAGE 2 PAGE 7 青海西宁地区乙型肝炎病毒感染现状及其血清标志物分析 摘要:目的：调查当前乙型肝炎病毒（HBV）的流行状况及其血清标志物的表现模式。 方法：采用酶联免疫吸附试验（ELISA）检测52062例血清标本中乙型肝炎病毒血清标志物（HBV-M）六项。 结果：人群中总阳性率为64.6748%，HBsAg阳性率为12.6753%，单独抗-HBs的阳性率为37.1672%，总抗-HBs的阳性率为48.8042%。阳性组中HBV-M共检测出28种模式，其中恢复期模式共7种，主要是：“2”“24”“245”“25”，占恢复期组构成比的83.4386%。感染期模式共21种，主要是：“145”“135”“15”，占感染期组构成比的95.3844%。结论：HBV的流行状况及其HBV-M模式均较以前发生了改变。单独抗-HBs阳性率为37.1672%，说明乙肝疫苗的接种取得了较好的预防效应，但仍存在大量的易感人群。HBV携带者的阳性率为12.6926%，高于以往文献中所报道的8%，说明乙型肝炎病毒的防治工作仍需进一步加强。HBV-M模式变得更为复杂，各模式人群检出率发生较大改变。调查当前HBV的流行状况及其血清标志物模式有助于更好的开展HBV的防治工作和提高临床免疫实验室检测水平。 关键词：乙型肝炎病毒；标志物；模式；酶联免疫吸附法 Report and qinghai xining region of HBV serum markers analysis Abstract：objective : The current survey of hepatitis B virus (HBV) prevalence and serum markers show mode. Methods: Enzyme-linked immunosorbent assay (ELISA) to detect serum samples 52,062 cases of hepatitis B virus serum markers (HBV-M) six. Results: The positive rate of population 64.6748%, HBsAg positive rate of 12.6753 percent, a separate anti--HBs positive rate of 37.1672%, the positive rate of 48.8042% total anti -HBs. Positive group HBV-M were detected in 28 kinds of models, a total of seven kinds of recovery mode, mainly: 2 24 245 25, representing 83.4386% recovery group consisting ratio. A total of 21 kinds of patterns of infection, mainly: 145, 135, 15, representing 95.3844% of the group consisting of infection ratio. Conclusion: HBV prevalence and HBV-M mode than in previous changed. The positive rate of anti -HBs alone 37.1672%, indicating that hepatitis B vaccination has achieved good preventive effect, but there are still a large number of vulnerable populations. The positive rate of HBV carriers is 12.6926%, higher than that reported in be strengthened. HBV-M models become more complex, the detection rate of the population in each mode change greatly. Investigation of the current prevalence of HBV and serum markers or contribute to a better prevention and control work HBV an