一线应用兔ATG联合CsA治疗儿童与年轻成人重型再生障碍性贫血.pdfVIP

中国协和医科大学 北京协和医学院 硕士研究生毕业(学位)论文 of ofchromatosome．6ientsunderwenttheretreatment pat rateof treatmentwas to66．7％． therapy．Theresponse secondary up Conclusion WeuserabbitATGincombinationofCsAforthetreatmentofchildren was with and adults consistentliterature young SAA／VSAA，theefficacy ofhorseATG+CsAasfirst—line thatotal rate reports therapy，wi response minoradversereactions．First—lineofrabbitATG of71％and application inthetreatmentofchildrenand adultsS从／VS从issafeandeffective． young WhetherrabbitATGcould treatment rateinadult improve response patients needsfurther investigation． [Key research 5 中国协和医科大学 北京协和医学院 硕士研究生毕业(学位)论文 英文缩略词表 ATG……anti-thymocyteglobulin…………………………抗胸腺细胞球蛋白 A………………………………………环孢素A CsA……ciclosporin anemia……………………………………再生障碍性贫血 从………aplastic IL………interleukin…………………………………………白介素 IFN……interferon…………………………………………干扰素 stemcell transplantation………造血干细胞移植 HSCT……hemopoietic therapy………………………免疫抑制治疗 IST……immunosuppressire HLA……human leucocyteantigen…………………………人类白细胞抗原 disease………………………移植物抗宿主疾病 GVHD……graft—versus—host SAA……severeanemia…………………………重型再生障碍性贫血 aplastic severe anemia……………………极重型再生障碍性贫血 VSAA……veryaplasric factor………粒细胞集落刺激因子 G-CSF…granulocytec010ny—sti刖1ating nocturnal PNH……