循证医学在心血管临床中的应用及科研设计.ppt

Patients were eligible for inclusion in ASCOT if they had hypertension (SBP ?160 mm Hg and/or DBP ?100 mm Hg [untreated] or SBP ?140 mm Hg and/or DBP ?90 mm Hg [treated]). Patients were also required to have ?3 risk factors for CHD, including: Smoking Left ventricular hypertrophy Specific ECG abnormalities Type 2 diabetes Peripheral vascular disease History of cerebrovascular event Male Age ?55 years Microalbuminuria/proteinuria TC:HDL ratio of ?6 History of early CHD in first-degree relative * The primary end point of nonfatal MI (including silent MI) and fatal CHD was significantly lower b