汤森路透医药信息解决方案讲义.ppt

Academic Researcher Pharmaceutical Industry Literature Patents Early File Application and Data Package Securities Exchange Commission Press release and Reports Industry Analyst Conference Scientific Meeting attend by physicians direct communication with the company Thomson Pharma Late 从支离破碎的片断→行业发展全貌的完整拼图 跟踪最新动态 跟踪某个靶标相关的新药物 跟踪新靶标、新Biomarker的出现 跟踪某个药物的新进展、不同国家上市情况 等等 结肠癌的信号转导 +K-Ras GDP EGF EGFR EGFR - Phosphate RAF MEK MAPK GTP GTP 细胞扩增 结肠癌的治疗: anti-EGFR antibodies +K-Ras GDP EGF EGFR EGFR - Phosphate RAF MEK MAPK GTP 细胞扩增 Panitumumab (Amgen) K-Ras mutation drives cell proliferation ind